Protein Targeted Therapeutics
By using cutting edge NMR experiments
coupled with modern high field NMR
spectrometers equipped with cryogenically cooled probes, we work with our partners by utilizing our proprietary technology to rapidly and efficiently deconvolute complex chemical and biological interactions that are often bottlenecks for research.
Interested in Protein Targeted Therapeutics Services?
NMR experiments can be tailored to specific biomolecules in order to elucidate ligand- target interactions under physiological and biologically relevant conditions. These methods can be leveraged to identify ligand binding sites as well as to monitor macromolecular dynamics as a function of ligand binding.
Maratech's Protein Targeted Therapeutics capabilities include:
Target conformational/structural analysis
Ligand binding site identification
Complete NMR-based 3D structure analysis
Kinetics and dynamics studies
Structure Activity Relationships
Dissociation constant (Kd) determination