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NMR is an indispensable tool in the development of therapeutics targeting novel RNA and DNA structures. It enables the determination of solution-state structures, identification of ligand binding sites, and measurement of the kinetics and affinities of ligand–RNA/DNA complexes.

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At Maratech NMR Solutions, our laboratories and instrumentation are purpose-built for RNA and DNA research, ensuring precision, reproducibility, and speed at every stage.

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• All RNA studies are conducted in RNase-free environments to preserve sample integrity.

• Our team brings deep expertise in construct design, ligand binding, and solution structure determination for novel RNA and DNA targets.

• With advanced NMR-based methods, we detect even the weakest molecular interactions under physiological conditions.

• Binding site identification provides mechanistic insights that guide the design of small-molecule therapeutics for RNA targets.

• We are recognized leaders in secondary structure determination of RNA and DNA.