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Complex Protein Structure
NMR Spectrometry Graph

About Maratech NMR Solutions

 

Who we are

Maratech NMR Solutions is a life sciences partner that specializes in state of the art Nuclear Magnetic Resonance Spectroscopy. We offer a wide range of services including both experimental and consulting support. Our scientists have over 20 years experience in the pharmaceutical industry advancing drug discovery research through the use of NMR. We work with our partners by utilizing our proprietary technology to rapidly and efficiently deconvolute complex chemical and biological interactions that are often bottlenecks for research. Maratech NMR Solutions also provides consulting support for organizations that have complex research problems where NMR spectroscopy may be of value or where high-level strategic input is needed.

  • We provide high quality NMR data that enables our clients to move their drug discovery research forward.

  • By using advanced deconvolution methodologies, we are able to work on the most complex of scientific problems.

  • Our modern methods and cutting edge technology allows for the lowest sample concentrations and fastest turnaround times in the industry.

  • The advantage is a faster turnaround time at an economical cost that we pass on to our partners.

NMR Instrumentation:

  • 500, 600 and two 800 MHz spectrometers with 

      cryogenically cooled probes with H, C, N, and F capability.

mRNA Structure

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Proteins/Peptides/RNA/DNA

  • Ligand binding site identification 

  • Complete NMR-based 3D structure analysis

  • Target conformational/structural analysis

  • Kinetics and dynamics studies

  • Structure Activity Relationships

RNA/DNA NMR Specific Capabilities

  • RNA/DNA structure solution determination 

  • Binding site identification 

  • RNA/DNA - target binding interactions 

  • NMR based screening methods

  • Structure Activity Analysis

  • RNA/DNA target constructs design suitable

    for solution structure studies

  • Screening of external libraries

  • Competition assays

  • Kinetics and dynamics studies

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Fragment and Small Molecule Screening

  • Ligand-observe methods (STD/waterlogsy NMR)

  • Target observe methods (HSQC/HMQC)

  • Competition assays

  • Dissociation constant (Kd) determination

  • Screening of external libraries

Small Molecule

  • Structural determination

  • Stability analysis

  • Complete Metabolite ID Structure

  • Metabolomics

NMR Spectrometry Visualization

Interested in Our Services?